Drug Efficacy Study Implementation
) was a program begun by the Food and Drug Administration
(FDA) in the 1960s after the requirement that all drugs
be efficacious as well as safe. The DESI program was intended to classify all pre-1962 drugs that were already on the market as either effective, ineffective, or needing further study.
The DESI program was a consequence of the Kefauver-Harris Drug Control Act.