Mandy left Tony but kept in contact with Dom. When Tony found this out he threw Dom out, Dom then returned to pick up clothes for Mandy, but decided against Mandy's wishes not to reveal her whereabouts to Tony, and told Tony where he could meet her, previously where Mandy had arranged to meet Dom so they could run off together. Tony met Mandy, and they talked, finally coming to the conclusion that it was probably for the best that they didn't see each other again, largely Mandy's decision. Tony was left in tears but slowly gets back to normality.
Mandy asked Dom to leave town with her, but he declined, due to loyalty towards his brother.
When Max Cunningham was named as a prime suspect in the attempt on his ex-wife Clare's life after she was pushed from the balcony in the Loft in June 2007, Dom was able to prove that Max was not involved in the attack, as he and Tony had seen Max in his flat around the time of the incident. Both of them had tried to persuade Max to come out for a drink for Dom's stag night that evening; but Max, traumatised by Tom being taken into care by Social Services because of a cruel trick by Clare, had refused to leave the flat and locked himself in. Tina had also seen Max leaving the Loft before the attack as he was asked to do so by Warren, because he had tried to confront Clare about Tom being taken into care. When Dom and Tony relayed this information during the police investigation, Max was released without any charges being brought against him.
Just before their wedding Tina found out about his old feelings for Mandy and didn't speak to him. But on the actual big day the two did wed after Louise burst in and announced that Mercedes slept with Warren on the night Clare was pushed.
One of the other reasons Dom and Tina became estranged was Dom forbidding Tina to carry a child for his brother and her sister, Jacqui. While he was in France, Tina got inseminated. When he returned, she told him what she had done and she refused to have an abortion. Dom went to confront Tony and claimed this was to get back at him because of what had happened with Mandy. Tony denied Dom's accusations and blasted him for not being a husband to Tina when she had needed him. Dom punched Tony, bloodying his nose, and stormed out of the flat. The next day, Dom begged Tony to convince Tina to have an abortion, but Tony refused. Dom wept in his arms.
With further thought, Dom decided to accept Tina's decision and they reconciled. However, as much as he supported Tina's wishes, he couldn't bring himself to be intimate with her, as all he could think of was her carrying his brother's child.
His insecurities only further worsened when he was accosted by a gang of teenage girls and had to be saved by Russ.