nitrous oxide

or laughing gas

Inorganic compound, one of the oxides of nitrogen. A colourless gas with a pleasantly sweetish odour and taste, it has an analgesic effect when inhaled; it is used as an anesthetic (often called just “gas”) in dentistry and surgery. This effect is preceded by mild hysteria, sometimes with laughter, hence the name laughing gas. It is also used as a propellant in food aerosols and as a leak detector.

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In enzymology, a NAD+-dinitrogen-reductase ADP-D-ribosyltransferase is an enzyme that catalyzes the chemical reaction

NAD+ + [dinitrogen reductase] rightleftharpoons nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]

Thus, the two substrates of this enzyme are NAD+ and [dinitrogen reductase], whereas its two products are nicotinamide and ADP-D-ribosyl-[dinitrogen reductase].

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase. Other names in common use include NAD-azoferredoxin (ADPribose)transferase, and NAD-dinitrogen-reductase ADP-D-ribosyltransferase.


  • Fitzmaurice WP, Saari LL, Lowery RG, Ludden PW, Roberts GP "Genes coding for the reversible ADP-ribosylation system of dinitrogenase reductase from Rhodospirillum rubrum". Mol. Gen. Genet. 218 340–7.
  • Lowery RG, Ludden PW "Purification and properties of dinitrogenase reductase ADP-ribosyltransferase from the photosynthetic bacterium Rhodospirillum rubrum". J. Biol. Chem. 263 16714–9.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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