Diet-induced obese

Diet-induced obese

Diet-induced obese (DIO) model, is a mouse model created to study obesity-related diseases such as diabetes. In this model, a mouse is fed a high fat diet, typically for 8 to 12 weeks. As a result it become obese, mildly to moderately hyperglycemic, and develop impaired glucose tolerance. These mice are then used to study the genetic and physiological mechanisms of obesity and type 2 diabetes.

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