Dexmedetomidine has sedative, analgesic, sympatholytic, and anxiolytic effects that blunt many of the cardiovascular responses in the perioperative period. It reduces the volatile anesthetic, sedative and analgesic requirements of the patient without causing significant respiratory depression.
Recent research has suggested dexmedetomidine to be an effective treatment for the dangerous cardiovascular symptoms of cocaine intoxication and overdose. It also seemed to be superior to lorazepam for ventilated patients in the intensive care unit.
DEXMEDETOMIDINE AS A SOLE SEDATING AGENT WITH LOCAL ANESTHESIA IN A HIGH-RISK PATIENT FOR AXILLOFEMORAL BYPASS GRAFT: A CASE REPORT
Oct 01, 2005; The α^sub 2^-agonist Dexmedetomidine is indicated for sedation of patients receiving mechanical ventilation in the...
Addition of Dexmedetomidine or Lornoxicam to Prilocaine in Intravenous Regional Anaesthesia for Hand or Forearm Surgery: A Randomized Controlled Study
Feb 01, 2009; Abstract Background and objectives: Intravenous regional anaesthesia (IVRA) is a simple and cost-effective technique that is...