Devilance appears in issue #7 of DC's weekly comic series 52, where he is substantially larger than he was portrayed in the past. He is on a remote alien planet where Starfire, Adam Strange and Animal Man are stranded. In issue #8, it is revealed that Devilance has captured Starfire. Adam Strange and Animal Man search for Starfire, but fall victim to his traps and are also captured.
Devilance's size is possibly due to an aspect of New Gods lore introduced by writer Peter David: the New Gods are all this size, and their worlds are proportionally sized. Boom-tubes resize objects traveling through them accordingly, but anyone who physically travels from the New God worlds to other physical worlds would notice the size difference. It is unknown if this idea has been retconned into the main continuity by other writers. This is connected to the fact that there is only one set of New Gods and New Gods worlds in all the multiverse.
In issue #9, (three days and two nights by in-story time), Devilance seems to believe the trio saw something only the gods (such as himself) were meant to. Thus, being "The God of the Pursuit", Devilance took it upon himself to catch them. The team manage to burn Devilance's face and escape his clutches. They also steal his Lance in hopes of using it as a power source for their space cruiser. Devilance is last seen bound by the very vines that once held his captives. It is also of note that, as Starfire stated during her escape, the whole planet they are on seems to be a trap set by Devilance himself.
In issue #17, he catches up with their spaceship, only to be eviscerated and decapitated by Lobo.