Definitions

DMT1

DMT1

DMT1 ("divalent metal transporter 1") is a transporter involved in human iron metabolism. It is located on the apical membrane of duodenal enterocytes and transports Fe2+ from the intestinal lumen to the cytosol.

Dietary iron must be reduced from Fe3+ to Fe2+ before being transported by DMT1. This is accomplished by Duodenal cytochrome B.

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