In 1988 Republican presidential candidate George H. W. Bush selected Quayle as his running mate. Although not taken seriously by the media at first, he became an effective speaker for conservative issues. He chaired the President's Council on Competitiveness, which attempted to reduce governmental and environmental regulation on businesses. Renominated in 1992, he attacked the "Hollywood" media and campaigned vigorously in defense of the Bush administration's record. Bush and Quayle lost the election to Bill Clinton and Al Gore. Quayle mounted an abortive run for the 2000 Republican presidential nomination in 1999.
See his memoir, Standing Firm (1994); R. F. Fenno, The Making of a Senator (1989); D. S. Broader and B. Woodward, The Man Who Would be President (1992).
See studies by J. F. Ragheb, ed. (1999) and M. Govan et al. (2004).
See biography by R. E. Cohen (1999).