1,5-anhydro-D-fructose reductase

1,5-anhydro-D-glucitol + NADP⁺ $rightleftharpoons$ 1,5-anhydro-D-fructose + NADPH + H⁺

Thus, the two substrates of this enzyme are 1,5-anhydro-D-glucitol and NADP⁺, whereas its 3 products are 1,5-anhydro-D-fructose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,5-anhydro-D-glucitol:NADP+ oxidoreductase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .

References

• Sakuma M, Kametani S and Akanuma H "Purification and some properties of a hepatic NADPH-dependent reductase that specifically acts on 1,5-anhydro-D-fructose". J. Biochem. 189–193.

External links

Gene Ontology (GO) codes