Cyclodextrin glucanotransferase

Cyclomaltodextrin glucanotransferase

In enzymology, a cyclomaltodextrin glucanotransferase is an enzyme that catalyzes the chemical reaction of cyclizing part of a 1,4-alpha-D-glucan molecule through the formation of a 1,4-alpha-D-glucosidic bond.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing). Other names in common use include Bacillus macerans amylase, cyclodextrin glucanotransferase, alpha-cyclodextrin glucanotransferase, alpha-cyclodextrin glycosyltransferase, beta-cyclodextrin glucanotransferase, beta-cyclodextrin glycosyltransferase, gamma-cyclodextrin glycosyltransferase, cyclodextrin glycosyltransferase, cyclomaltodextrin glucotransferase, cyclomaltodextrin glycosyltransferase, konchizaimu, alpha-1,4-glucan 4-glycosyltransferase, cyclizing, BMA, CGTase, and neutral-cyclodextrin glycosyltransferase.

Structural studies

As of late 2007, 47 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , and .

References

  • DePinto JA, Campbell LL "Purification and properties of the amylase of Bacillus macerans". Biochemistry. 7 114–20.
  • Wild GM "Studies on the Schardinger dextrins. VII. Co-substrate specificity in coupling reactions of Macerans amylase". J. Am. Chem. Soc. 76 2387–2390.
  • Hehre EJ "Enzymic synthesis of polysaccharides: a biological type of polymerization". Adv. Enzymol. Relat. Subj. Biochem. 11 297–337.
  • SCHWIMMER S "Evidence for the purity of Schardinger dextrinogenase". Arch. Biochem. Biophys. 43 108–17.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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