A patient with Cuboid Syndrome usually seeks medical advice and attention complaining of pain, discomfort, or weakness in their foot, usually experienced during sporting exertion or impact, such as landing from a jump. The pain may be observed in a controlled environment by standing on the toes or rolling the arches of the foot, as these motions tend to exercise the foot's calcaneocuboid joint and ligament, which are characteristically strained in a patient suffering from Cuboid Syndrome. Also, the pain may come on suddenly or it may develop gradually and persist over time. Sometimes the pain is intermittent, subsiding partially or completely for a period of time before returning again.
A patient may develop Cuboid Syndrome through either a single injury event or repetitive strain over time. The condition mainly affects athletes, especially those whose activities incur a significant amount of pressure on their feet from jumping or running (such as ballet dancers and runners) and those who place added strain on their feet during lateral maneuvering (such as tennis and basketball players). Cuboid Syndrome may persist even if the patient is taking part in regular physical therapy. The patient's foot type, such as the presence of overpronation or underpronation, may also play a factor in the condition.
Once diagnosed, a medical professional may treat Cuboid Syndrome by realigning (also known as reducing) the subluxed cuboid. This form of manual manipulation of the foot should be done by a trained specialist, such as a podiatrist. Further treatment may take into account other considerations, such as possible causes or aggravators (e.g. recommending that the patient be fit with custom orthotics if she is overprone). Fortunately, subluxed cuboids are generally quite treatable and most patients return to a normal level of activity once the pain is brought under control.