In a study by Yoshihara et al. 60% of pediatric asthmatic patients demonstrating acute symptoms were found to have creola bodies in their sputum (CB+). These patients had increased levels of neutrophil-mediated cytokine activity concluding that "epithelial damage is associated with a locally enhanced chemotactic signal for and activity of neutrophils, but not eosinophils, during acute exacerbations of paediatric asthma."
Research from California National Primate Research Center Reveals New Findings on Extracellular Matrix Proteins.
Apr 26, 2011; Investigators publish new data in the report 'Reduction of collagen VII anchoring fibrils in the airway basement membrane zone of...