Industrial accidents, such as the Bhopal disaster, Halifax Explosion, Texas City Disaster, and Oppau explosion have caused mass casualties.
Technical means of verification, including space-based sensors that can scan large parts of the world, can provide early warning of long-range missile development. Space-based Staring Infrared Sensors can detect the heat of rocket launching motors. Various radars can monitor range and other characteristics, but they need to be in a place where they have line-of-sight to the missile trajectory. The United States, probably Russia, and possibly other nations have aircraft-based and ship-based sensors that can monitor such tests, but there has to be warning of potential tests so these sensors can be deployed.