This is called the "countable chain condition" rather than the more logical term "countable antichain condition" for historical reasons related to complete Boolean algebras. (If κ is a cardinal, then in a complete Boolean algebra every antichain has size less than κ if and only if there is no descending κ-sequence of elements, so chain conditions are equivalent to antichain conditions.)
A topological space is said to satisfy the countable chain condition if the partially ordered set of non-empty open subsets of X satisfies the countable chain condition, i.e. if every pairwise disjoint collection of non-empty open subsets of X is countable.
Every separable topological space is ccc. Every metric space which is ccc is also separable, but in general a ccc topological space need not be separable.
For example,
with the product topology is ccc but not separable.
Ccc partial orders and spaces are used in Martin's Axiom.
In the theory of forcing, ccc partial orders are used because forcing with any generic set over such an order preserves cardinals and cofinalities.
More generally, if κ is a cardinal then a poset is said to satisfy the κ-chain condition if every antichain has size less than κ. The countable chain condition is the ℵ1-chain condition.