In the previous year, the number of teams participating was reduced to only 42: the teams in Serie A and Serie B. For 2008-09, that number was expanded to 78 with the addition of 18 clubs from Lega Pro Prima Divisione (formerly Serie C1), 9 clubs from Lega Pro Seconda Divisione (formerly Serie C2) and 9 clubs from Serie D. Also, except for the semi-finals, all rounds are one-leg fixtures. The one-game final played at the Stadio Olimpico in Rome, which was first adopted in 2007-08, remains.
Throughout the tournament, home stadium advantage is given to the projected higher seed (i.e., assuming no upsets). In the two-leg semifinals, the projected higher seed plays the second leg at home.
|Round of 16|
|Benevento||Bassano Virtus||Portogruaro||Real Marcianise|
Due to financial problems and other sanctions, the list of 78 teams was filled as follows:
1 The match was played and Cremonese won by a score of 1–0, but were later disqualified for using a player who should have been under suspension. Reggiana was awarded a 3–0 victory as a result.