The municipality Colombey-les-Deux-Eglises was created administratively in 1793, and it became part of the district of Chaumont and the canton Blaise. In 1801, under the name Colombey, it passed to the canton Juzennecourt. In 1972, it absorbed the communes Argentolles, Biernes, Blaise, Champcourt, Harricourt, Pratz and Lavilleneuve-aux-Fresnes.
De Gaulle withdrew repeatedly to Colombey as his political fortunes waned; first on the establishment of the Fourth Republic in 1946, and then between 1953 and 1958 before he became President again at the height of the Algerian Crisis. His final withdrawal to Colombey came in 1969 and he died there the following year. Colombey became widely used as a political metaphor for a statesman's temporary withdrawal from political life, until his country would come calling for him again.