Chorda tympani is a branch of the facial nerve (the seventh cranial nerve) that serves the taste buds in the front of the tongue, runs through the middle ear, and carries taste messages to the brain.
The chorda tympani is part of one of three cranial nerves that are involved in taste. The taste system involves a complicated feedback loop, with each nerve acting to inhibit the signals of other nerves. The chorda tympani appears to exert a particularly strong inhibitory influence on other taste nerves, as well as on pain fibers in the tongue. When the chorda tympani is damaged, its inhibitory function is disrupted, leading to less inhibited activity in the other nerves.
The nerve continues through the petrotympanic fissure, after which it emerges from the skull into the infratemporal fossa. It soon combines with the larger lingual nerve, a branch of the mandibular nerve (cranial nerve V3).
The fibers of the chorda tympani travel with the lingual nerve to the submandibular ganglion.
Here, the preganglionic parasympathetic fibers of the chorda tympani synapse with postganglionic fibers which go on to innervate the submandibular and sublingual salivary glands.
Special sensory (taste) fibers also extend from the chorda tympani to the anterior 2/3rds of the tongue via the lingual nerve.