Born in Cresco, Iowa, his early career was as a cartoonist on the Mutt and Jeff series of cartoons for the Barré Studio. By the late 20s, he was starring in his own series of slapstick comedies for R-C Pictures and Educational Pictures. His slapstick comedies, a few of which have survived, are an amazing mixture of live action and animation created with the "Bowers Process." Complex Rube Goldberg gadgets also appear in many of his comedies. Two notable films include Now You Tell One with a memorable scene of elephants marching into the U.S. Capitol, and There It Is, a surreal mystery involving the Fuzz-Faced Phantom and MacGregor, a cockroach detective. He made a few sound films such as It's a Bird and Wild Oysters, and wrote and illustrated children's books in his later years. For eight years during the 1930s he lived in Wayne, New Jersey, and drew cartoons for the Jersey Journal.
His work, long forgotten, has undergone a rediscovery and revival of interest in recent years. His 15 surviving films were the subject of a 2004 two-DVD release by Image Entertainment and Lobster Films of France.