Definitions

Cefradine

Cefradine

{{drugbox | | IUPAC_name = (6R,7R)-7-{[(2R)-2-amino-2-(1-cyclohexa-1,4-
dienyl)acetyl]amino}-3-methyl-8-oxo-5-thia-
1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = Cefradine.svg | CAS_number = 38821-53-3 | ATC_prefix = J01 | ATC_suffix = DB09 | PubChem = 38103 | DrugBank = | C = 16 | H = 19 | N = 3 | O = 4 | S = 1 | molecular_weight = 349.406 g/mol | bioavailability = Well absorbed | protein_bound = <10% | metabolism = Nil | elimination_half-life = 0.9 hours | excretion = Renal, unchanged | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_status = Rx-only | routes_of_administration = Oral, IM, IV }} Cefradine (INN) or cephradine (former BAN) is a first generation cephalosporin antibiotic.

Indications

It has similar spectrum of activity to cefalexin.

Dosage

Dosage by mouth for adults is 250–500 mg every 6 hours, or 500 mg to 1 g every 12 hours. In severe infections up to 1 g every 6 hours may be used. Dosages for children are based upon their weight with 25–50 mg/kg total daily dose given in 2–4 divided doses.

Formulations

Capsules containing 250 mg or 500 mg, Syrup containing 250 mg/5 ml, or vials for injection containing 500 mg or 1 g.

References

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