Since 48Ca is both stable and neutron-rich, it is a valuable starting material for the production of new nuclei in particle accelerators, both by fragmentation and by fusion reactions with other nuclei, for example in the recent production of ununoctium. Heavier nuclei generally require a greater fraction of neutrons for maximum stability, so neutron-rich starting materials are necessary.
48Ca is the lightest nucleus known to undergo double beta decay and the only one simple enough to be analyzed with the sd shell model. It also releases more energy (4.27 MeV) than any other double beta decay candidate. These properties make it an interesting probe of nuclear structure models and a promising candidate in the ongoing search for neutrinoless double beta decay.