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CYP2B6
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CYP2B6

CYP2B6
CYP2B6 is a member of the Cytochrome P450 group of enzymes. Along with CYP2A6, it is involved with metabolizing nicotine, along with many other substances.

CYP2B6 Ligands

Substrates Inhibitors Inducers
Often mentioned :
Bupropion (antidepressant)
Cyclophosphamide (Alkylating antineoplastic agent)
Efavirenz (NNRTI)
Ifosfamide (Alkylating antineoplastic agent)
Other:
Alfentanil (opioid analgesic)
Nevirapine (NNRTI)
Propofol (anesthetic)
tamoxifen (SERM)
Valproic acid (anticonvulsant , mood-stabilizing)
Artemisinin (against malaria)
Pethidine (analgesic)
Nicotine (stimulant)
Modafinil (stimulant-like)
Sertraline (SSRI)
thiotepa (Alkylating antineoplastic agent)

Strong :
Orphenadrine (analgesic)
unspecified:
Paroxetine (SSRI)
fluoxetine (SSRI)
Estradiol (sex hormone)
Phencyclidine (dissociative)
ritonavir (antiretroviral)
sertraline (SSRI)
thiotepa (Alkylating antineoplastic agent)
ticlopidine (antiplatelet)

 Often mentioned :
carbamazepine (anticonvulsant, mood stabilizer)
rifampicin (bactericidal) Other:
artemisinin (against malaria)
clotrimazole (antifungal)
ifosfamide (Alkylating antineoplastic agent)
glucocorticoids (antiinflammatory)
phenobarbital (anticonvulsant )
phenytoin (antiepileptic)
ritonavir (antiretroviral)

References

External links

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Last updated on Saturday October 04, 2008 at 23:14:23 PDT (GMT -0700)
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