In business:

• Coombs, Phillips and Lisansky, the founders of CPL Business Consultants
• Cost per Lead, associated with the Pay per Lead Marketing method.
• NYSE stock symbol of CPFL Energia

Certifications:

• Certified Professional Landman, a designation awarded by the American Association of Professional Landmen
• Certified Professional Locksmith, a designation awarded by the Associated Locksmiths of America
• Certified Professional Logistician, a designation awarded by the International Society of Logistics

In computer science:

• A Control Panel (Windows) File (*.cpl) under Windows 95, NT, and newer
• In computer science, Current privilege level
• The Call-Processing Language: An XML-based language used to describe and control Internet telephony services
• The Combined Programming Language: a computer programming language developed jointly between the Mathematical Laboratory at the University of Cambridge and the University of London Computer Unit during the 1960s

Libraries:

• The Chicago Public Library System, which has 79 branches in the city of Chicago
• Coquitlam Public Library, a public library in Coquitlam, British Columbia
• The Cleveland Public Library, which includes a Main Library in downtown Cleveland, and 28 branches throughout the city.
• Codices Palatini latini, the collection of Latin manuscripts in the Palatine library in Heidelberg.

Licenses:

• A Commercial Pilot Licence
• A Concealed Pistol License. Otherwise known as a CCW or CHL depending on the state.
• The Common Public License: an open source license from IBM

In sports:

• The Central Plains League, a high school athletic league in Central Kansas comprised mainly of mid-sized, rural schools with two recently joining private school members. Although it is known mainly as one of the state's toughest football leagues, the CPL has produced state champions in a wide variety of sports.
• The Cyberathlete Professional League: a competitive video game league

In transport:

• CPL is the ICAO airline designator for Chaparral Airlines, United States

In finance:

• CPL is closing protection letter written by escrow/title company to lender.

Other:

• Center for Progressive Leadership
• Chemical Physics Letters, a chemical physics journal published frequently by Elsevier.
• Complementary Pass-transistor Logic, one of many logic families
• Corporal (Cpl), a military rank
• Filter (photography), Circular Polarizer Filter
• The Criminal Procedure Law (in the State of New York)
• The Communist Party of Latvia
• The Communist Party of Lebanon
• The Communist Party of Lithuania
• With petrol and diesel prices, cpl stands for cents per litre.
• Capillary Pumped Loop, a passive thermal device similar to a Loop heat pipe
• Automotive:Critical Part List