, a CDP-4-dehydro-6-deoxyglucose reductase
is an enzyme
the chemical reaction
- CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD(P)+ + H2O CDP-4-dehydro-6-deoxy-D-glucose + NAD(P)H + H+
The 4 substrates of this enzyme are CDP-4-dehydro-3,6-dideoxy-D-glucose, NAD+, NADP+, and H2O, whereas its 4 products are CDP-4-dehydro-6-deoxy-D-glucose, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on CH or CH2 group with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase. Other names in common use include CDP-4-keto-6-deoxyglucose reductase, cytidine diphospho-4-keto-6-deoxy-D-glucose reductase, cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase, CDP-4-keto-deoxy-glucose reductase, CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system, and NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase. This enzyme participates in starch and sucrose metabolism.
- Pape H, Strominger JL "Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. V Partial purification of the two protein components required for introduction of the 3-deoxy group". J. Biol. Chem. 244 3598–604.
- Rubenstein PA, Strominger JL "Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 8 Mechanistic roles of enzyme E-1 and pyridoxamine 5'-phosphate in the formation of cytidine diphosphate-4-keto-3,6-dideoxy-D-glucose from cytidine diphosphate-4-keto-6-deoxy-D-glucose". J. Biol. Chem. 249 3776–81.
- Liu HW, Thorson JS "Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria". Annu. Rev. Microbiol. 48 223–56.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes