During the show's public debut on April 25 2005, it promised to deliver "5 or so" minutes of Tom & Molly's take on tech news every second day, but it has evolved into 35-45 minutes of daily tech-related banter and commentary. As early as 30 March 2005, Molly and Tom were discussing subjects such as: patent infringement lawsuits, the Apple iPod, and DRM. In 2006, they produced a video episode of Buzz Out Loud at the San Francisco premiere of Snakes on a Plane. At CES 2007, video of the Buzz Out Loud podcast recording sessions were streamed live on CNET TV. On 21 May 2007, Jason Howell joined the podcast as producer. On 3 December 2007, the hosts commented on the controversy over the firing of Gamespot's Jeff Gerstmann.
"Buzztown" is a fictional city in which the listeners of Buzz Out Loud are the residents, and is similar to a real city in that it has a mayor. . Listeners are also referred to as "The Buzz Brigade" or "The Buzz Militia".
The show was used as an example in an O'Reilly article on how to rewrite a podgrabber.
In November 2005, the show gained Earthlink as a sponsor. This marked the beginning of a period of continuity for the show, as most episodes have featured the trio of commentators. The exceptions usually involve one of the commentators being unavailable to record due to business trips, sick days, or vacations. In late March 2006, Buzz Out Loud switched to a new Earthlink sponsorship, having 11 different ads instead of the previous 1. Earthlink eventually ended their sponsorship at the beginning of 2008, and the program went unsponsored for five months. On May 1, Best Buy became the sponsor of the program, featuring a similar ad pattern as Earthlink.
The show occasionally features interviews; initially, these were integrated as a part of the show, but they have since been spun off into separate episodes due to listener requests. Tech luminaries such as Lawrence Lessig and Steve Wozniak have been interviewed, as well as several hosts of the TWiT.tv and Revision3 networks.
Every so often, the Buzz Out Loud crew records live shows at technology trade shows, such as recordings done from the Consumer Electronics Show (CES), and Macworld. These live shows can include a live audience, comprised of fans of the show, and discussions on the different products that the commentators have seen at the shows. Other times, one of the hosts will attend a live event, such as Molly at the former E3, and instead call in to the show before, during or after the event with updated information.
A video edition of the podcast had been experimented on and off with several services, until the Friday-only video edition within a dedicated studio was launched officially on CNET TV with the May 2 episode. As of Episode 797, this version has been abandoned in favor of a recorded version of the USTREAM video.
A former running gag in the show is that each day is an official US holiday, though the holidays cited are often whimsical in nature. The holidays are cited from the Bizarre American Holidays calendar
After many listener suggestions, they decided to have four hosts for each show, alternating guest hosts each day. Frequent guests include Natali Del Conte, Brian Tong, Brian Cooley, and Rafe Needleman.