He was born in Glenbuck Scotland and was a member of the Glenbuck Cherrypickers, playing alongside members of his extended family. He played as a wing-half, and his professional clubs included Rangers (1891-1894), Preston North End (1894-1899) and Portsmouth (1899-1901).
He became player–manager of Portsmouth in 1901. Portsmouth won the 1901-02 Southern League title under Blyth. After retiring from his post as manager, he later served Portsmouth as director and chairman.
His brother William Blyth also played for Portsmouth, and his son Robert Blyth played for both Portsmouth and Southampton in the 1920s. His sister, Barbara, was mother of Bob Shankly and Bill Shankly.