, a benzoyl-CoA 3-monooxygenase
is an enzyme
the chemical reaction
- benzoyl-CoA + NADPH + H+ + O2 3-hydroxybenzoyl-CoA + NADP+ + H2O
The 4 substrates of this enzyme are benzoyl-CoA, NADPH, H+, and O2, whereas its 3 products are 3-hydroxybenzoyl-CoA, NADP+, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating). This enzyme is also called benzoyl-CoA 3-hydroxylase.
- Niemetz R, Altenschmidt U, Brucker S, Fuchs G "Benzoyl-coenzyme-A 3-monooxygenase, a flavin-dependent hydroxylase Purification, some properties and its role in aerobic benzoate oxidation via gentisate in a denitrifying bacterium". Eur. J. Biochem. 227 161–8.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes