He was born in Pistoia in 1474, and adopted the name Rovezzano from the quarter of Florence in which he lived.
His most important works include:
Pope Leo X sent twelve terra cotta medallions by Rovezzano to Cardinal Wolsey. The sculptor himself went to England in 1524. Wolsey commissioned a tomb for himself, but fell from royal favour before its completion, but King Henry VIII of England ordered its completion. King Charles I of England wished to be buried in it although it remained empty until Nelson was buried in it.