Bayamo is the capital city of the Granma Province of Cuba, and one of the largest cities in the Oriente region.
The community of Bayamo lies on a plain by the Bayamo River. It is affected by the violent Bayamo wind.
The municipality is divided into the barrios of Arroyo Blanco, Barrancas, Bueycito, Cauto, Cayamas, Cristo, Dátil, Guamo, Guisa, Hornos, Julia, Laguna Blanca, La Sal, San Juan and Veguita.
The main secondary education institution is the University of Granma.
A tremendous flood, in 1616, choking the Cauto with trees and wrecked vessels, cut if off from direct access to the sea; but through Manzanillo it continued a great clandestine traffic with Curaçao, Jamaica, and other foreign islands throughout the 17th and 18th centuries. Bayamo was then surrounded by fine plantations.
In 1827 it acquired the status of city. In the war of 1868–1878 it was an insurgent stronghold; near it was fought one of the most desperate conflicts of the war, and it was nearly destroyed by the opposing parties.