O'Rourke may refer to several different people:

People

• Andrew O'Rourke, judge and politician from New York State
• Beto O'Rourke (born 1973), American entrepreneur and civic leader
• Brian O'Rourke (1540 – 1591), hereditary lord of West Breifne in Ireland
• Colm O'Rourke (born 1957), Irish footballer
• Danny O'Rourke (born 1983), American soccer player
• Declan O'Rourke, Irish singer
• Dennis O'Rourke (born 1945), Australian documentary film director
• Derval O'Rourke (born 1981), Irish sprint hurdles athlete
• Edward O'Rourke (1876-1943), Polish Roman Catholic priest, bishop of Riga, first bishop of Danzig (Gdańsk)
• Frank O'Rourke (1916 – 1989), American writer
• Frank O'Rourke (baseball) (1894 – 1986), Canadian infielder in Major League Baseball
• Frank O'Rourke (footballer) (1878 – 1954), Scottish footballer
• Heather O'Rourke (1975 – 1988), American child actress
• Jim O'Rourke (baseball player) (1850 - 1919), American professional baseball player
• Jim O'Rourke (musician) (born 1969), American musician and producer
• John O'Rourke (1849 - 1911), 19th century baseball player
• Joseph O'Rourke, a disambiguation page
• Mary O'Rourke (born 1937), Irish politician
• Mícéal O'Rourke, an Irish classical pianist
• Michael O'Rourke (born 1955), New Zealand javelin thrower
• Michael James O'Rourke (1878 - 1957), Canadian recipient of the Victoria Cross
• P. J. O'Rourke (born 1947), American political satirist, journalist, and writer
• Patrick Henry O'Rourke (1837 - 1863), Irish-born Civil War colonel
• Peter O'Rourke (1874 – 1956), Scottish footballer and manager
• Sean O'Rourke, Irish journalist and broadcaster
• Steve O'Rourke (1940 - 2003), manager of rock band Pink Floyd
• Tammy O'Rourke (born 1971), child dancer and actress
• TS O'Rourke (born 1968), Irish author

See also

• Laing O'Rourke, a construction firm in the UK
• Walton and O'Rourke, a famous team of cabaret puppeteers
• O'Rorke
• Rourke