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6-O-methylnorlaudanosoline 5'-O-methyltransferase

In enzymology, a 6-O-methylnorlaudanosoline 5'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline rightleftharpoons S-adenosyl-L-homocysteine + nororientaline

Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-O-methylnorlaudanosoline, whereas its two products are S-adenosylhomocysteine and nororientaline.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.


  • Rueffer M, Nagakura N, Zenk MH "A highly specific O-methyltransferase for nororientaline synthesis isolated from Argemone platyceras cell cultures". Planta Med. 49 196–198.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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