, an aryl-aldehyde dehydrogenase (NADP+)
is an enzyme
the chemical reaction
- an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O an aromatic acid + NADPH + H+ + ATP
The 5 substrates of this enzyme are aromatic aldehyde, NADP+, AMP, diphosphate, and H2O, whereas its 4 products are aromatic acid, NADPH, H+, and ATP.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is aryl-aldehyde:NADP+ oxidoreductase (ATP-forming). Other names in common use include aromatic acid reductase, and aryl-aldehyde dehydrogenase (NADP+).
- Gross GG "Formation and reduction of intermediate acyladenylate by aryl-aldehyde. NADP oxidoreductase from Neurospora crassa". Eur. J. Biochem. 31 585–92.
- Gross GG, Zenk MH "[Reduction of aromatic acids to aldehydes and alcohols in the cell-free system. 1. Purification and properties of aryl-aldehyde: NADP-oxidoreductase from Neurospora crassa]". Eur. J. Biochem. 8 413–9.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes