Apamea or
Apameia (Απάμεια) was a
Hellenistic city on the left bank of the
Euphrates, opposite the famous city of
Zeugma, at the end of a bridge of boats (Greek:
zeugma) connecting the two, founded by
Seleucus I Nicator (
Pliny, v. 21). The city was rebuilt by
Seleucus I. The site, once partially covered by the village of
Tilmusa (formerly Rum-Kala),
Şanlıurfa Province,
Turkey, is now flooded by the lake formed by the
Birecik Dam (Birejik Dam).
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