3,7-dimethylquercetin 4'-O-methyltransferase

S-adenosyl-L-methionine + 5,3',4'-trihydroxy-3,7-dimethoxyflavone $rightleftharpoons$ S-adenosyl-L-homocysteine + 5,3'-dihydroxy-3,7,4'-trimethoxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,3',4'-trihydroxy-3,7-dimethoxyflavone, whereas its two products are S-adenosylhomocysteine and 5,3'-dihydroxy-3,7,4'-trimethoxyflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase. Other names in common use include flavonol 4'-O-methyltransferase, flavonol 4'-methyltransferase, 4'-OMT, S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone, 4'-O-methyltransferase, and 3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt].

References

• De Luca V, Ibrahim RK "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases". Arch. Biochem. Biophys. 238 596–605.
• De Luca V, Ibrahim RK "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases". Arch. Biochem. Biophys. 238 606–18.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes