In enzymology, an alkylhalidase is an enzyme that catalyzes the chemical reaction

bromochloromethane + H2O rightleftharpoons formaldehyde + bromide + chloride

Thus, the two substrates of this enzyme are bromochloromethane and H2O, whereas its 3 products are formaldehyde, bromide, and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is alkyl-halide halidohydrolase. Other names in common use include halogenase, haloalkane halidohydrolase, and haloalkane dehalogenase.


  • Heppel LA and Porterfield VT "Enzymatic dehalogenation of certain brominated and chlorinated compounds". J. Biol. Chem. 176 763–769.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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