• Leo D'Amato, a fictional character in the television series Veronica Mars
• Phil D'Amato, a fictional NYPD forensic detective

People with the surname D'Amato:

• Al D'Amato (born 1937), former New York politician
• Armand Paul D'Amato (21st century), American politician
• Brian D'Amato (21st century), American author and sculptor
• C. Richard D'Amato (21st century), American attorney
• Cus D'Amato (1908-1985), Italian-American sportsperson
• Frank D'Amato (born 1947), Italian-American mobster
• Giovanni Antonio D'Amato the younger (circa 1535-1598), Italian painter
• Joe D'Amato (1936-1999), Italian director
• John D'Amato (died 1992), Italian-American mobster
• Lisa D'Amato (born 1980), American fashion model
• Mike D'Amato (born 1962), American politician
• Mike D'Amato (American football) (born 1943), American college and professional football player
• Peter D'Amato (21st century), American businessperson