Tlacacuitlahuatzin was the first tlatoani (ruler) of Tiliuhcan, a pre-Columbian Tepanec altepetl (ethnic state) near Tlacopan.
His daughters Miyahuaxochtzin and Matlalxochtzin married Huitzilihuitl and Tlatolzaca (respectively), sons of Acamapichtli, the first tlatoani of Tenochtitlan. Another daughter, Tlacochcuetzin, married Acolnahuacatl Tzaqualcatl, the first tlatoani of Tlacopan.
Upon his death, Tlacacuitlahuatzin was succeeded by Tzihuactlayahuallohuatzin, a son of Tezozomoc, the ruler of Azcapotzalco.
- Chimalpahin Cuauhtlehuanitzin, Domingo Francisco de San Antón Muñón (1997). Codex Chimalpahin: society and politics in Mexico Tenochtitlan, Tlatelolco, Texcoco, Culhuacan, and other Nahua altepetl in central Mexico: the Nahuatl and Spanish annals and accounts collected and recorded by don Domingo de San Antón Muñón Chimalpahin Quauhtlehuanitzin. Norman: University of Oklahoma Press.