Acetylacetone-cleaving enzyme

pentane-2,4-dione + O₂ $rightleftharpoons$ acetate + 2-oxopropanal

Thus, the two substrates of this enzyme are pentane-2,4-dione and O₂, whereas its two products are acetate and 2-oxopropanal.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is acetylacetone:oxygen oxidoreductase. Other names in common use include Dke1, acetylacetone dioxygenase, diketone cleaving dioxygenase, and diketone cleaving enzyme.

References

• Straganz GD, Glieder A, Brecker L, Ribbons DW, Steiner W "Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii". Biochem. J. 369 573–81.

External links

The CAS registry number for this enzyme class is .