Definitions
Acetyl&o=10616

N-acetylneuraminate 4-O-acetyltransferase

In enzymology, a N-acetylneuraminate 4-O-acetyltransferase is an enzyme that catalyzes the chemical reaction

acetyl-CoA + N-acetylneuraminate rightleftharpoons CoA + N-acetyl-4-O-acetylneuraminate

Thus, the two substrates of this enzyme are acetyl-CoA and N-acetylneuraminate, whereas its two products are CoA and N-acetyl-4-O-acetylneuraminate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase. This enzyme is also called sialate O-acetyltransferase.

References

  • Schauer R "[Biosynthesis of N-acetyl-O-acetylneuraminic acids. I. Incorporation of (14C) acetate into sections of the submaxillary salivary gland of ox and horse]". Hoppe. Seylers. Z. Physiol. Chem. 351 595–602.
  • Schauer R "[Biosynthesis of N-acetyl-O-acetylneuraminic acids. II. Substrate and intracellular localization of bovine acetyl-coenzyme A: N-acetylneuraminate-7- and 8-O-acetyltransferase]". Hoppe. Seylers. Z. Physiol. Chem. 351 749–58.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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