From the south, it enters the city from Daly City and runs north through the Crocker-Amazon, Excelsior, Bernal Heights, and Inner Mission neighborhoods. From there the road turns northeast and travels through the South of Market neighborhood (running a full block south of Market Street) before ending at the Embarcadero in downtown San Francisco.
In the South of Market portion of the street, new high rises have risen along the street like the 40-story The Paramount, the 26-story 101 Second Street, the 31-story JP MorganChase Building and the 42-story St. Regis Museum Tower. More high rises are planned or are under construction like the Millennium Tower, 555 Mission Street, and the massive San Francisco Transbay development.
It is served 24 hours a day by the Muni line 14; two BART stations are directly under it in the Inner Mission; all the rest of San Francisco's BART stations are less than a mile away from it. The street is four lanes wide.
|San Mateo||Daly City||Continuation beyond F Street|
|North end of SR 82 overlap|
|San Francisco||Central Freeway||Interchange; no entrance ramps|
|North end of US 101 overlap|
|The Embarcadero||Former SR 480|