The wing provides base and en route support for Department of Defense, allied nations and other authorized aircraft in transit, including those from the Netherlands, Belgium, Canada, France, Italy, Colombia, Germany, Venezuela and Great Britain.
The 65th conducted reserve training toward proficiency with troop carrier aircraft from 1952-1953. However, the wing was never fully manned or equipped.
It has provided enroute support for aircraft transiting Lajes Air Base from 1982 to the present. The wing also provided base support to elements of the U.S. Army and U.S. Navy in the area. The 65th supported deployment of personnel and equipment through Lajes during operations in the Persian Gulf from August 1990-April 1991 and in support of Operation Enduring Freedom and Operation Iraqi Freedom since 2001 and 2003 respectively.
65th Mission Support Group (65 MSG)
65th Medical Group (65 MDG)