, a 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase
is an enzyme
the chemical reaction
- (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hexadec-2-enoyl-[acyl-carrier-protein] + H2O
Hence, this enzyme has one substrate, (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein], and two products, hexadec-2-enoyl-[acyl-carrier-protein] and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase (hexadec-2-enoyl-[acyl-carrier protein]-forming). Other names in common use include D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase, beta-hydroxypalmitoyl-acyl carrier protein dehydrase, beta-hydroxypalmitoyl thioester dehydratase, beta-hydroxypalmityl-ACP dehydrase, and (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase. This enzyme participates in fatty acid biosynthesis.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .
- Mizugaki M, Swindell AC, Wakil SJ "Intermediate- and long-chain beta-hydroxyacyl-ACP dehydrases from E coli fatty acid synthetase". Biochem. Biophys. Res. Commun. 33 520–7.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes