Walter Simmons, Earnest Reese, Tom Motlow, Herbert Gannaway and E.L. Woolf were the starters in the first game on December 15, 1900. After trailing 16-4 at halftime, the Commodores outscored the Y 15-4 in the second half to pull within 20-19, before losing 22-19. Vanderbilt routed the Y in the second game in February, 1901 by a score of 24-9. They secured a win in the deciding game in March, 1901 on a late goal 14-12.
The Commodores played the final game of their inaugural season against the Nashville Athletic Club, whose players were older and bigger. After trailing 10-5 at halftime, Walter Simmons, a four-year starter on the football team, led the Commodores back, but NAC won 13-11.
|December 15, 1900||at Nashville Y.M.C.A.||Nashville, TN||L 19-22||0-1||-|
|February, 1901||at Nashville Y.M.C.A.||Nashville, TN||W 24-9||1-1||-|
|March, 1901||at Nashville Y.M.C.A.||Nashville, TN||W 14-12||2-1||-|
|March, 1901||at Nashville Athletic Club||Nashville, TN||L 11-13||2-2||-|