He is the elder child and only son of Ian Campbell, 12th Duke of Argyll and Iona Mary Colquhoun, daughter of Captain Ivar Iain Colquhoun, 8th Baronet of Luss, and was educated at Cargilfield, Glenalmond, the Royal Agricultural College and McGill University. He was a Page of Honour to HM The Queen from 1981–1983, and became a sales agent, salesman, and company manager. He is the Master of the Household (ranking 25th in the Scottish order of precedence), Admiral of the Western Coasts and Isles, and the chief of Clan Campbell.
The duke is the captain of Scotland's national elephant polo team which won the 2004 and 2005 World Elephant Polo Association world championships. He also works for Pernod Ricard, promoting Scotch whiskies such as Glenlivet and Chivas Regal.
On June 8 2002, he married Eleanor Cadbury, a descendant of the Cadbury chocolate dynasty. They have two sons, Archibald Frederick Campbell, Marquess of Lorne and Lord Rory James Campbell (born 2006). They are expecting their third child in November.